Wednesday, February 24, 2010

Application of Computer Sc. on human Genetics=Bioinformatics

Bioinformatics is the application of information technology and computer science to the field of molecular biology.
In 1979 Paulien Hogeweg who coined the term “Bioinformatics“. Its primary use since at least the late 1980s has been in genomics and genetics, particularly in those areas of genomics involving large-scale DNA sequencing.
For last few decades fast development in the field genomic and other molecular research technologies and developments in information technologies have joint to produce a tremendous amount of information related to molecular biology.
The field of bioinformatics has evolved such that the most vital assignment now involves the analysis and interpretation of various types of data, including nucleotide and amino acid sequences, protein domains, and protein structures.

Goal of Bioinformatics.
The primary goal of bioinformatics is to increase our understanding of biological processes and main activities of bioinformatics comprise mapping and analyzing DNA and protein sequences, aligning different DNA and protein sequences to compare them and creating and viewing 3-D models of protein structures

Major research hard work in the field include sequence alignment, gene finding, genome assembly, drug design, drug discovery, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, genome-wide association studies and the modeling of evolution.

No comments:

Post a Comment